![]() We propose that, like protein-coding genes, miRNA genes involved in male reproduction are subject to rapid adaptive changes that may contribute to functional novelties during evolution. ![]() The expression analysis in rhesus monkeys revealed a strong correlation between miRNA expression changes and male sexual maturation, suggesting regulatory roles of this miRNA cluster in testis development and spermatogenesis. In addition, lineage-specific substitutions were observed in human and chimpanzee, leading to the emergence of potential novel mature miRNAs. There is no need to reconvert your images. Upgrade at any time for features like fullscreen viewing, complete Toolbar options, bookmarking, and slideshows. And Zoomify is completely compatible with all Zoomify products. Our data indicate rapid evolution of this cluster in primates including frequent tandem duplications and nucleotide substitutions. Zoomify includes everything you need to start - drag-drop Converter, simple image Viewer, and template web page. Here we sequenced and compared this miRNA cluster in major primate lineages including human, great ape, lesser ape, Old World monkey, and New World monkey. var rect new Rect (image.RenderSize) var bounds image.TransformToAncestor (border).TransformBounds (rect) Share. You could easily check if the bounds are located inside the Border control. The sum of two complex numbers, where the real numbers do not equal zero, results in a sum of 34i. The following code gives you the bounds of the transformed Image control in coordinates relative to the Border control. Recently, an X-linked miRNA cluster was reported with multiple copies in primates but not in rodents or dog. The length of a rectangle is three times the width. ![]() However, nonconserved miRNAs may contribute to functional novelties during evolution. Most of the identified miRNAs are highly conserved among species, indicating strong functional constraint on miRNA evolution. MicroRNAs (miRNAs) are a growing class of small RNAs (about 22 nt) that play crucial regulatory roles in the genome by targeting mRNAs for cleavage or translational repression.
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